DNA and Protein Sequence Analysis

DNA Probes and Sequence Analysis

A gene probe, CAP-21, which demonstrated interrelationships between the members of the Mycoplusma mycoides cluster w a s developed. The probe easily differentiated mycoplasmas in this cluster by clear and predictable hybridization patterns in Southern blots and separated the cluster into four groups. Strains of M. mycoides subsp, mycoides which were capable of causing contagious bovine pleuropn...

DNA Sequence Analysis using

Adaptive resonance theory (ART) describes a class of artiicial neural network architectures that act as classiication tools which self-organize, work in real-time, and require no retraining to classify novel sequences. We have adapted ART networks to provide support to scientists attempting to categorize tandem repeat DNA fragments from Onchocerca volvulus. In this approach, sequences of DNA fr...

Enhancement of DNA and Protein Sequence

Databases of protein and DNA sequences are growing at an alarming rate as biologists map entire genomes. Improved methods of analyzing these data are necessary. One method currently in use is the dot matrix plot. These plots provide a complete picture of similarity between two DNA or protein sequences. These similarities indicate homology (similar evolution), which provides critical information...

DNA sequence and a protein sequence or pro le

Locating protein coding exons on a genomic DNA sequence is the initial and di cult step of predicting functions of the genes embedded in that part of the genome. Recent rapid development in this area has attained an accuracy of nearly 80 % for correctly predicting coding exons (CDSs) in mammalian genes [1]. However, for homology modeling of a protein structure, for example, we need perfectly ac...

Characterization of Avian Pasteurella multocida Isolates by Protein Profiles and Restriction Enzyme Analysis of Chromosomal DNA